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Ponen en venta prueba casera para detección del cáncer colorrectal 31 Oct 2014


Strict Standards: Non-static method SimplePie_Misc::get_element() should not be called statically, assuming $this from incompatible context in /home/cubaheal/public_html/classes/simplepie/simplepie.inc on line 13264

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Estados Unidos puso en venta Cologuard, la primera prueba casera colorrectal de análisis de las heces para detectar la presencia de glóbulos rojos y mutaciones en el ADN que pueden indicar la presencia de tumores anormales.
indexLa prueba, aprobada en agosto pasado por la Administración de Alimentos yFármacos (FDA), detecta hemoglobina, la molécula de una proteína que constituye uno de los componentes de la sangre.

Cologuard también detecta ciertas mutaciones relacionadas con el cáncer colorrectal en el ADN de las células que desprenden los adenomas avanzados, conforme las heces se mueven a través del intestino grueso y el recto.

Los pacientes cuya prueba arroja un resultado positivo deben someterse a una colonoscopía diagnóstica.

El c√°ncer colorrectal afecta principalmente a las personas de 50 a√Īos de edad y mayores y se encuentra entre los tipos de c√°ncer que atacan tanto a hombres como a mujeres.

Se trata del tercer c√°ncer m√°s com√ļn y la segunda causa de muerte por c√°ncer en Estados Unidos.

La prueba de detecci√≥n del c√°ncer colorrectal es eficaz para reducir las tasas de enfermedad y muerte relacionadas con el c√°ncer de colon, se√Īal√≥ la agencia.

Los Centros de Control de Enfermedades (CDC) calculan que si toda persona mayor de 50 a√Īos se hiciera la prueba de detecci√≥n regularmente, como se recomienda, por lo menos 60 % de las defunciones por c√°ncer colorrectal podr√≠an evitarse.
octubre 30/2014 (Notimex)

Tomado del Bolet√≠n de Prensa Latina Copyright 2014 “Agencia Informativa Latinoamericana Prensa Latina S.A.

Mutaciones genéticas explican convulsiones febriles por vacuna combinada 31 Oct 2014


Strict Standards: Non-static method SimplePie_Misc::get_element() should not be called statically, assuming $this from incompatible context in /home/cubaheal/public_html/classes/simplepie/simplepie.inc on line 13264

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Investigadores daneses han descubierto que¬† existe una predisposici√≥n gen√©tica que puede explicar por qu√© algunos ni√Īos¬† pueden sufrir convulsiones febriles tras haber recibido la vacuna combinada SPR¬† (sarampi√≥n, paperas y rub√©ola).

Las convulsiones febriles se producen en los peque√Īos con motivo de fiebres¬† altas y pueden durar de uno a cinco minutos, antes de que el ni√Īo recupere su¬† estado normal. En general, la crisis no se reproduce ni tiene consecuencias en¬† el cerebro.

Dichas convulsiones no están relacionadas con una crisis de epilepsia, que  se produce en ausencia de fiebre.

En un estudio publicado por la revista brit√°ncia “Nature¬† Genetics“, los investigadores han mostrado que alrededor de un ni√Īo de cada¬† 1000 presentan convulsiones febriles despu√©s de recibir esta vacuna triple¬† v√≠rica.

Para Bjarke Feenstra, principal autor del estudio, no se puede cuestionar¬† la eficacia de esta triple vacuna “que evita la muerte de un mill√≥n de ni√Īos¬† cada a√Īo en el mundo”.

“Los resultados de los estudios como el nuestro deber√≠an llevar a la¬† creaci√≥n de vacunas todav√≠a m√°s seguras”, exhort√≥ en un correo electr√≥nico a la¬† AFP.

Al estudiar el perfil gen√©tico de 1300 ni√Īos daneses que han tenido¬† convulsiones febriles tras recibir la triple vacuna y compararlos con 5800¬† ni√Īos que no hab√≠an sido vacunados y 2000 que tuvieron convulsiones no¬† vinculadas con la vacuna, los investigadores han identificado varias mutaciones¬† gen√©ticas que favorecen las convulsiones.

Dos de ellas est√°n relacionadas con los genes que desempe√Īan un papel¬† importante en la manera en que el sistema inmunitario reacciona a los ataques¬† virales.

Otros cuatro afectan a los genes que gobiernan los canales iónicos  implicados en el funcionamiento de las neuronas.

Seg√ļn el estudio, los ni√Īos que presentan las cuatro √ļltimas mutaciones¬† tienen cerca de cuatro veces m√°s de riesgo de tener convulsiones febriles que¬† los ni√Īos que no los tienen.

No obstante, los investigadores revelan que las seis mutaciones¬† descubiertas hasta ahora solo representan una peque√Īa parte de causas gen√©ticas¬† susceptibles de favorecer las convulsiones.

Subrayan tambi√©n que las mutaciones solo se han estudiado en los ni√Īos¬† daneses y que no saben si existen los mismos riesgos en otras partes.

En 1998, un estudio publicado en la revista m√©dica brit√°nica “The Lancet”¬† hab√≠a sembrado el p√°nico en el mundo anglosaj√≥n al relacionar la vacuna triple¬† con el autismo.

Aunque el art√≠culo fue retirado despu√©s debido a “irregularidades”, el¬† temor sobre esta vacuna persiste entre los padres que¬† muchos se niegan a¬† vacunar a sus hijos, sobre todo en Gran Breta√Īa.
octubre 30/2014  (AFP)

Tomado del Bolet√≠n de Prensa Latina Copyright 2014 “Agencia Informativa Latinoamericana Prensa Latina S.A.

Est√≥magos, los √ļltimos organoides hechos con c√©lulas en el laboratorio 31 Oct 2014


Strict Standards: Non-static method SimplePie_Misc::get_element() should not be called statically, assuming $this from incompatible context in /home/cubaheal/public_html/classes/simplepie/simplepie.inc on line 13264

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A la lista de tejidos humanos tridimensionales fabricados en el laboratorio para emular diferente √≥rganos, se acaban de a√Īadir los est√≥magos. Un grupo de cient√≠ficos del Hospital Infantil de Cincinnati ha desarrollado una versi√≥n en miniatura del est√≥mago humano a partir de c√©lulas madre pluripotentes. El trabajo se publica en “Nature“.

estomagoides_1Esta primera generaci√≥n de organoides g√°stricos tridimensionales humanos ofrece¬† nuevas oportunidades para el estudio de f√°rmacos en desarrollo y para mejorar la comprensi√≥n de las primeras fases del c√°ncer g√°strico, as√≠ como de la diabetes tipo 2, entre otras enfermedades, seg√ļn destaca Jim Wells, principal investigador del estudio y cient√≠fico de las divisiones de Biolog√≠a del Desarrollo y Endocrinolog√≠a en el Hospital de Cincinnati.

De hecho, y en colaboraci√≥n con investigadores de la Universidad de Cincinnati, el equipo de Wells ha generado los organoides g√°stricos para poder estudiar la infecci√≥n por “Helicobacter pylori”, principal causa de √ļlcera p√©ptica y c√°ncer de est√≥mago.

Los modelos animales no son los id√≥neos para estudiar enfermedades como la citada infecci√≥n bacteriana, recuerdan los autores del trabajo, puesto que hay marcadas diferencias anat√≥micas y que ata√Īen al funcionamiento de los √≥rganos entre especies. Los organoides son estructuras complejas, tridimensionales y contienen diferentes tipos de c√©lulas humanas que los acercan a las caracter√≠sticas funcionales de los tejidos humanos.

“Hasta ahora, nadie hab√≠a generado c√©lulas g√°stricas a partir de c√©lulas madre pluripotentes humanas”, apunta Wells, y destaca que tambi√©n es la primera vez que se logra producir un primordio del est√≥mago. Con esta t√©cnica podr√≠an obtenerse otros primordios, de pulm√≥n o p√°ncreas, por ejemplo, para identificar las causas que conducen a una formaci√≥n an√≥mala de los √≥rganos.

“Helicobacter pylori”
La primera enfermedad que han estudiado con este nuevo modelo de investigaci√≥n es la infecci√≥n por “H. pylori”. A los cient√≠ficos les ha llamado la atenci√≥n c√≥mo en 24 horas la bacteria indujo cambios bioqu√≠micos en los tejidos epiteliales del est√≥mago. Entre los efectos, destacaron la activaci√≥n del gen asociado al c√°ncer c-Met, as√≠ como una r√°pida expansi√≥n del pat√≥geno por el epitelio.
octubre 30/2014 (Diario Médico)

 

El √Čbola en Sierra Leona no es m√°s letal que anteriores brotes 31 Oct 2014


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Los datos confirman que las dimensiones de la actual epidemia del √©bola no deben atribuirse a un pat√≥geno m√°s agresivo, sino a la debilidad de las medidas de control. En Sierra Leona, donde junto a Liberia y Guinea contin√ļa la expansi√≥n de forma m√°s intensa, el periodo de incubaci√≥n y la tasa de fatalidad es similar a la observada en otras regiones afectadas por el brote actual, as√≠ como en otros previos.

Es la principal conclusión a la que llega un grupo de epidemiólogos, de la Universidad de Tulane, en Nueva Orleans, y del Grupo de Respuesta de la Organización Mundial de la Salud, tras analizar las muestras clínicas y de laboratorio de 106 pacientes en Sierra Leona entre mayo y junio.

Seg√ļn publican en “The New England“, el periodo de incubaci√≥n se sit√ļa entre los 6 y 12 d√≠as, y la tasa de mortalidad en el 74 %. La presentaci√≥n de la enfermedad incluye fiebre en el 89 % de los pacientes; dolor de cabeza (80 %); debilidad (66 %); mareos (60 %); diarrea (51%); dolor abdominal (40 %), y v√≥mitos (34 %o). Los menores de 21 a√Īos tuvieron una tasa de mortalidad menor que los mayores de 45 (57 frente a 94 %), al igual que aquellos con menos de 100 000 copias del virus por mil√≠litro, comparados con los que superaban la cifra (33 y 94 %). Solo un paciente refiri√≥ hemorragias.

Las conclusiones del estudio conectan con la idea, expuesta hasta la saciedad por quienes trabajan en el brote, sobre la necesidad de aumentar los esfuerzos para controlar el virus en √Āfrica, idea que tambi√©n refleja el cient√≠fico Tim Inglis, de la Univerisidad Western Australia, en un art√≠culo de opini√≥n en “Nature”.
octubre 30/2014 (Diario Médico)

¬ŅPor qu√© rascarse produce que te pique m√°s? 31 Oct 2014


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El picor y el rascado se cree que es un mismo c√≠rculo vicioso. La investigaci√≥n, publicada en la revista “Neuron“, proporciona nuevas pistas que pueden ayudar a romper ese ciclo, sobre todo en personas que experimentan picaz√≥n cr√≥nica.

Los cient√≠ficos han sabido durante d√©cadas que el picor crea una cantidad leve de dolor en la piel, dijo el investigador principal, Zhou-Feng Chen, director del Centro para el Estudio del picor de la Universidad de Washington. Ese dolor puede interferir, al menos temporalmente, por implicar c√©lulas nerviosas de la m√©dula espinal para transmitir las se√Īales de dolor al cerebro en lugar de las se√Īales de picaz√≥n.

Esta es la primera vez que la liberación de neurotransmisores cerebrales se han relacionado con el picor, dijo Chen.

Como parte del estudio, los cient√≠ficos criaron una cepa de ratones que carecen de los genes para producir serotonina. Cuando estos ratones modificados gen√©ticamente fueron inyectados con una sustancia que normalmente produce el picor en la piel, los ratones no se rascaban tanto como sus compa√Īeros de camada normales. Pero cuando los ratones alterados gen√©ticamente fueron inyectados con la serotonina, se rascaban como se esperaba en respuesta a compuestos dise√Īados para inducir el picor.

Aunque la interferencia con la serotonina produce menos sensibilidad al picor, Chen dijo que no es práctico intentar tratar la picazón bloqueando la liberación de serotonina.
octubre 30/2014 (Diario Médico)

Desarrollan en Italia fármaco para contener los síntomas del ébola 30 Oct 2014


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Beatrice Lorenzin, ( ministra de Salud de Italia), anunció recientemente  que su país desarrolló un fármaco que bloquea hemorragias y puede ser eficaz contra los síntomas del ébola.
Explicó que el producto se clasifica como antihemorrágico, por lo que se utiliza para tratar uno de los principales síntomas de la enfermedad, pero no combate el virus.

Recordó que por ahora los pacientes son tratados con terapias de apoyo, porque no existen medicinas específicas contra el ébola, ni tampoco vacunas.

El compuesto, preparado por el Instituto Qu√≠mico Farmac√©utico Militar (IQFM), termin√≥ los ensayos cl√≠nicos fase 1, y ser√° enviado a Sierra Leona, uno de los pa√≠ses de √Āfrica occidental m√°s afectados por la epidemia. Lorenzin explic√≥ que la medicina fue desarrollada mientras se estudiaba un antihemorr√°gico con fines militares, en particular contra heridas, pero demostr√≥ ser eficaz tambi√©n contra los s√≠ntomas del √©bola.

“En caso de que se compruebe su eficacia podr√≠an ser enviadas otras dosis al oeste de √Āfrica, donde tiene su foco la epidemia”.
Por otra parte, Elhadj As Sy, secretario general de la Federación Internacional de Cruz Roja y Media Luna Roja, afirmó  que es posible contener la epidemia de ébola en un periodo de cuatro a seis meses.

Se√Īal√≥ que esa meta de contenci√≥n del virus del √Čbola puede alcanzarse con el cumplimiento de principios b√°sicos como “buen aislamiento, buen tratamiento de los casos confirmados y enterramientos seguros para las v√≠ctimas mortales”.
El virus afecta con mayor impacto Liberia, Sierra Leona y Guinea. De acuerdo con el m√°s reciente reporte de la OMS, m√°s de nueve mil 191 personas fueron infectadas, de las cuales unas cuatro mil 546 murieron.
http://www.granma.cu/salud

 
 
 
Clínica Central Cira García
IPK (Instituto de Medicina Tropical)
IPK (Instituto de Medicina Tropical)
INOR
Instituto Nacional de Oncológica y Radiobiologia
Ciren
CIREN(Centro Internacional de Restauración Neurológica).
Centro de Salud La Pradera
Centro Internacional de Salud La Pradera
 
Cubandhealth.com :.: Todos lo derechos reservados. 2013
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